Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defence system. Additionally, cell fusions participate in tissue repair and may be important to cancer development, progression and therapy. A large number of factor
Analysis of the role of egg integrins in sperm-egg binding and fusion
✍ Scribed by Yuji Takahashi; Naomi Yamakawa; Kazuya Matsumoto; Yutaka Toyoda; Kiyoshi Furukawa; Eimei Sato
- Book ID
- 111659627
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 445 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1040-452X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The effects of temperature (4–37°C) on sperm‐egg fusion and the post‐fusion events were studied. At 4–10°C, acrosome‐reacted spermatozoa bound to egg plasma membranes, but could not fuse with them. At 25°C or above, both binding and fusion took place. The post‐fusion events could occur
Phospholipase A 2 (PLA 2 ), its localization on human sperm and its involvement in sperm-egg interaction, was investigated. Sperm-egg interaction was examined using an in vitro assay of the interaction between human sperm and zona-free or zona-intact hamster egg. PLA 2specific antibodies and/or lyso