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Analysis of the Prostate Cancer–Susceptibility Locus HPC20 in 172 Families Affected by Prostate Cancer

✍ Scribed by Cathryn H. Bock; Julie M. Cunningham; Shannon K. McDonnell; Daniel J. Schaid; Brett J. Peterson; Robert J. Pavlic; Jennifer J. Schroeder; Jason Klein; Amy J. French; Angela Marks; Stephen N. Thibodeau; Ethan M. Lange; Kathleen A. Cooney


Book ID
117853555
Publisher
American Society of Human Genetics
Year
2001
Tongue
English
Weight
401 KB
Volume
68
Category
Article
ISSN
0002-9297

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## Abstract Three putative prostate cancer–susceptibility genes, __RNASEL/HPC1__ at 1q24, __MSR1__ at 8p22, and __ELAC2/HPC2__ at 17p11, have recently been identified. Our objective was to investigate somatic mutations in these genes in sporadic prostate cancer. We analyzed 39 clinical prostate can