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Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1

โœ Scribed by Dunsmuir, WD; Edwards, SM; Lakhani, SR; Young, M; Corbishley, C; Kirby, RS; Dearnaley, DP; Dowe, A; Ardern-Jones, A; Kelly, J


Book ID
109838691
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
722 KB
Volume
78
Category
Article
ISSN
0007-0920

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## Abstract Three putative prostate cancerโ€“susceptibility genes, __RNASEL/HPC1__ at 1q24, __MSR1__ at 8p22, and __ELAC2/HPC2__ at 17p11, have recently been identified. Our objective was to investigate somatic mutations in these genes in sporadic prostate cancer. We analyzed 39 clinical prostate can