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Analysis of the methylation patterns of thep16INK4A,p15INK4B, andAPCgenes in gastric adenocarcinoma patients from a Brazilian population

✍ Scribed by Bárbara do Nascimento Borges, Rommel Mario Rodriguez Burbano…


Book ID
120719478
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
356 KB
Volume
34
Category
Article
ISSN
1010-4283

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## Silencing of p16 INK4a by methylation of the CpG islands in the promoter region has been found to be an alternative mechanism of inactivation in several tumors. However, in gastric carcinoma, the relationship between methylation status and the transcriptional silencing of the p16 gene remains t