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Analysis of the limitations of hepatitis B surface antigen expression in soybean cell suspension cultures

โœ Scribed by T. R. Ganapathi; G. B. Sunil Kumar; L. Srinivas; C. J. Revathi; V. A. Bapat


Publisher
Springer
Year
2007
Tongue
English
Weight
490 KB
Volume
26
Category
Article
ISSN
0721-7714

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The human hepatoblastoma-derived cell line HB6 I I secretes hepatitis-B surface antigen (HBsAg) and hepatitis-B e antigen (HBeAg) into the medium. Hepatitis-B-virus(HBV) DNA integrated into the cellular genome was found to be hypermethylated. When the cells were treated with 5-azacytidine for 3 days