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Analysis of the fragile-X chromosome: localization and detection of the fragile site in high resolution preparations

✍ Scribed by M. S. Krawczun; E. C. Jenkins; W. T. Brown

Publisher
Springer
Year
1985
Tongue
English
Weight
441 KB
Volume
69
Category
Article
ISSN
0340-6717

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Using a nonair-drying modification of a method for longitudinal sectioning of metaphase spreads on glass slides [Wen et al., 1997], we have studied 14 preidentified X chromosomes (10 from fragile X specimens and 4 controls) with transmission electron microscopy (TEM). Four of 10 X chromosomes from f