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Analysis of the D1S80 (pMCT118) VNTR locus polymorphism in a native Kuwaiti population by the polymerase chain reaction

✍ Scribed by Khaled E. Al-Nassar; Jancy Mathew; Nancy Thomas; Hasmukh R. Fatania

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 754 KB
Volume: 78
Category: Article
ISSN: 0379-0738
DOI: 10.1016/0379-0738(95)01881-6

No coin nor oath required. For personal study only.

✦ Synopsis

We have determined the allele and genotype frequencies at the hypervariable locus D1S80 in a native Kuwaiti population using the polymerase chain reaction technique and subsequent high resolution gel electrophoresis. In a sample of 200 individuals, 21 alleles and 57 genotypes were detected. The alleles with 18 and 24 repeat units were most common with frequencies of 0.188 and 0.408 respectively. The distribution of the observed genotypes was in agreement with the Hardy-Weinberg equilibrium prediction. The observed heterozygosity for the population sample was 0.80 with the allelic diversity of 0.781 +/- 0.029 and the power of discrimination was 0.94. The data obtained in this study are potentially useful for individual identification in forensic casework.

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