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Analysis of the angiotensin-converting enzyme inhibitors perindopril, lisinopril, and quinapril by HPLC

✍ Scribed by G. M. Khomushku; A. A. Zhloba; V. S. Puchnin; M. V. Arkhipova; S. M. Moiseeva

Publisher
Springer
Year
2011
Tongue
English
Weight
143 KB
Volume
44
Category
Article
ISSN
0091-150X

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✍ S. Rimar; C.N. Gillis πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier 🌐 English βš– 502 KB

Lisinopril is a potent competitive inhibitor of purified rabbit lung ACE (dissociation t1/2 = 105 min). To examine reversibility of binding and ACE functional activity in situ, the single-pass extraction (E) of an 125I-lisinopril analogue (351A) and the hydrolysis of an ACE substrate, benz-phe-ala-p