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Analysis of T cell receptor-gene rearrangement in T cells from the cerebrospinal fluid of patients with multiple sclerosis

✍ Scribed by Francien T.M. Rotteveel; Ingrid Kokkelink; Harm K. van Walbeek; Chris H. Polman; Jacques J.M. van Dongen; Cornelis J. Lucas


Book ID
119106857
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
631 KB
Volume
15
Category
Article
ISSN
0165-5728

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To better characterize the inflammatory response that occurs in the nervous system in multiple sclerosis (MS), T-cell receptor (TCR) gene expression was quantified from cerebrospinal fluid (CSF) cells of 21 patients with active disease. Unstimulated CSF cells expressed each of 22 different TCR beta