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Analysis of streptozotocin-induced incomplete chromosome elements and excess acentric fragments in Chinese hamster cells using a telomeric PNA probe

✍ Scribed by Alejandro D. Bolzán; Martha S. Bianchi

Book ID: 113808550
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 128 KB
Volume: 570
Category: Article
ISSN: 0027-5107
DOI: 10.1016/j.mrfmmm.2004.11.008

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## Abstract Fluorescence in situ hybridization (FISH) with a telomeric peptide nucleic acid probe was employed to analyze the induction of incomplete chromosome elements (ICE; i.e., incomplete chromosomes and terminal fragments) by bleomycin (BLM) in two mammalian cell lines. Chinese hamster embryo