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Analysis of sister chromatid exchanges in fra(X) individuals

✍ Scribed by Gregory, Paula ;Wang, Nancy ;Howard-Peebles, Patricia N. ;Opitz, John M. ;Reynolds, James F.

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
153 KB
Volume
23
Category
Article
ISSN
0148-7299

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This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m