Analysis of secondary structure in proteins by chemical cross-linking coupled to MS
✍ Scribed by Mariana Fioramonte; Aline Mara dos Santos; Sean McIIwain; William S. Noble; Kleber G. Franchini; Fabio C. Gozzo
- Book ID
- 115560980
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 832 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1615-9853
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📜 SIMILAR VOLUMES
## Abstract The fragmentation behavior of a novel thiourea‐based cross‐linker molecule specifically designed for collision‐induced dissociation (CID) MS/MS experiments is described. The development of this cross‐linker is part of our ongoing efforts to synthesize novel reagents, which create either
The organization of select proteins within ribonucleoprotein particles containing heterogeneous nuclear and uridine-rich small nuclear RNAs (hnRNP and UsnRNP respectively) was examined by chemical cross-linking and ribonuclease digestion using diagonal two dimensional PAGE and immunoblotting detecti