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Analysis of rocuronium in human plasma by liquid chromatography–tandem mass spectrometry with application in clinical pharmacokinetics

✍ Scribed by de Moraes, Natália Valadares; Lauretti, Gabriela Rocha; Filgueira, Gabriela Campos de Oliveira; Lopes, Bruno Carvalho Portes; Lanchote, Vera Lucia

Book ID
122138761
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
541 KB
Volume
90
Category
Article
ISSN
0731-7085

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## Abstract A rapid and sensitive LC/MS/MS assay was developed and validated for the determination of clopidogrel in human plasma. Clopidogrel was extracted by single liquid–liquid extraction with pentane, and chromatographic separations were achieved on a C~18~ column. The method was validated to