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Determination of tolperisone in human plasma by liquid chromatography/tandem mass spectrometry for clinical application

✍ Scribed by Chang-Ik Choi; Jung-In Park; Hye-In Lee; Yun-Jeong Lee; Choon-Gon Jang; Jung-Woo Bae; Seok-Yong Lee

Book ID
119289335
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
362 KB
Volume
911
Category
Article
ISSN
1873-376X

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## Abstract A rapid and sensitive LC/MS/MS assay was developed and validated for the determination of clopidogrel in human plasma. Clopidogrel was extracted by single liquid–liquid extraction with pentane, and chromatographic separations were achieved on a C~18~ column. The method was validated to