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Analysis of pyramidal neuron morphology in an inducible knockout of brain-derived neurotrophic factor

✍ Scribed by Justin J. Hill; Nutan Kolluri; Takanori Hashimoto; Qiang Wu; Allan R. Sampson; Lisa M. Monteggia; David A. Lewis

Book ID
119196689
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
114 KB
Volume
57
Category
Article
ISSN
0006-3223

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## Abstract The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) lumen triggers ER stress. ER stress initiates a number of specific compensatory signaling pathways including unfolded protein response (UPR). UPR is characterized by translational attenuation, synthesis