Analysis of PTEN Mutation in Non-familial Pheochromocytoma
β Scribed by JANUSZ PUC; GRZEGORZ PLACHA; BOZENNA WOCIAL; KATRINA PODSYPANINA; RAMON PARSONS; ZBIGNIEW GACIONG
- Book ID
- 111479560
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 385 KB
- Volume
- 1073
- Category
- Article
- ISSN
- 0890-6564
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Recently, a putative tumor suppressor gene, PTEN/MMAC1, has been identified at chromosome 10q23.3, which encodes a 403 amino acid dual-specificity phosphatase containing a region of homology to tensin and auxillin. Somatic mutations of the PTEN/MMAC1 gene have been identified in a number of cancer c