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Analysis of Polysorbate 80 and its Related Compounds by RP-HPLC with ELSD and MS Detection

✍ Scribed by Zhang, R.; Wang, Y.; Tan, L.; Zhang, H. Y.; Yang, M.

Book ID: 111879779
Publisher: Preston Publications
Year: 2012
Tongue: English
Weight: 474 KB
Volume: 50
Category: Article
ISSN: 0021-9665
DOI: 10.1093/chromsci/bms035

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## Abstract A sensitive and selective high‐performance liquid chromatographic assay for the quantiﬁcation of ketanserin and ketanserinol in human plasma was developed and validated. The procedure involves extraction of ketanserin and ketanserinol from plasma using an Extrelut NT‐1 solid‐phase extra