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Analysis of polyglutamine-coding repeats in the TATA-binding protein in different neurodegenerative diseases

✍ Scribed by Y. R. Wu; H. C. Fung; G. J. Lee-Chen; K. Gwinn-Hardy; L. S. Ro; S. T. Chen; H. M. Hsieh-Li; H. Y. Lin; C. Y. Lin; S. N. Li; C. M. Chen

Publisher
Springer
Year
2004
Tongue
English
Weight
91 KB
Volume
112
Category
Article
ISSN
1435-1463

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Analysis of polyglutamine-coding repeats
Analysis of polyglutamine-coding repeats in the TATA-binding protein in different human populations and in patients with schizophrenia and bipolar affective disorder
✍ Rubinsztein, David C.; Leggo, Jayne; Crow, Timothy J.; DeLisi, Lynn E.; Walsh, C πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 411 KB πŸ‘ 3 views

## ~ A new class of disease (including Hunting ton disease, Kennedy disease, and spinocerebellar ataxias types 1 and 3) results from abnormal expansions of CAG trinucleotides in the coding regions of genes. In all of these diseases the CAG repeats are thought to be translated into polyglutamine tr