A systematic analysis of disease-associated variants in the 3′ regulatory regions of human protein-coding genes II: the importance of mRNA secondary structure in assessing the functionality of 3′ UTR variants

PDGF B mRNA variants in human tumors wit

PDGF B mRNA variants in human tumors with similarity to the v-sis oncogene: Expression of cellular PDGF B protein is associated with exon 1 divergence, but not with a 3'UTR splice variant

✍ Susanne Heller; Lena Scheibenpflug; Bengt Westermark; Monica Nistér 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 418 KB 👁 2 views

While platelet-derived growth factor, PDGF, is not regularly expressed in mesenchymal tissues, PDGF B mRNA is often found in tumors derived from these tissues. PDGF B protein is also present, but the protein levels in individual tumors do not appear to correlate well with those of the mRNA. PDGF B i