To better address the need for developing stable formulations of plasmid DNA-based biopharmaceuticals, 37 compounds from a generally regarded as safe library were examined for their potential use as stabilizers. A plasmid DNA-based therapeutic vaccine, BHT-DNA, was used as a model system. Initial st
β¦ LIBER β¦
Analysis of plasmid DNA from a pharmaceutical perspective
β Scribed by C. Russell Middaugh; Robert K. Evans; Donna L. Montgomery; Danilo R. Casimiro
- Book ID
- 109388958
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 178 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Identifying stabilizers of plasmid DNA f
β
Yuhong Zeng; Joshua D. Ramsey; Robert King; Michael Leviten; Ruth Mcguire; David
π
Article
π
2011
π
John Wiley and Sons
π
English
β 452 KB
Industrial Scale cGMP Purification of Ph
β
J. Urthaler; W. Buchinger; R. Necina
π
Article
π
2005
π
John Wiley and Sons
π
English
β 339 KB
## Abstract The advances in gene therapy and genetic vaccination based on plasmid DNA result in an increasing demand of pharmaceutical grade plasmids produced under cGMP. A generic process consisting of a cell disintegration step followed by three different chromatography steps has been developed.
Preparation of pharmaceutical-grade plas
β
Franc Smrekar; AleΕ‘ Podgornik; Mateja Ciringer; Sandra Kontrec; Peter Raspor; Al
π
Article
π
2010
π
Elsevier Science
π
English
β 640 KB
DNA-DNA hybridization analysis of Strept
β
George A. Somkuti; Dennis H. Steinberg
π
Article
π
1991
π
John Wiley and Sons
π
English
β 597 KB
Advances in chromatographic supports for
β
Γngela Sousa; Fani Sousa; JoΓ£o A. Queiroz
π
Article
π
2012
π
John Wiley and Sons
π
English
β 644 KB
Development of technology for purificati
β
E. A. Volosnikova; N. I. Akulova; Ya. S. Gogina; G. M. Levagina; V. K. Mikhailov
π
Article
π
2010
π
SP MAIK Nauka/Interperiodica
π
English
β 671 KB