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Analysis of p53 codon 72 polymorphism and its association with human papillomavirus 16 and 18 E6 in Chinese cervical lesions

โœ Scribed by H. MIN-MIN; X. MING-RONG; C. ZE-YI; Y. KAI-XUAN; S. ZHI-LIN


Book ID
109085943
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
99 KB
Volume
16
Category
Article
ISSN
1048-891X

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## Abstract Human papillomavirus (HPV) infects the squamous epithelial cells of oral cavity and cervix leading to formation of warts that develops into the cancer. Human papillomavirus (HPV)โ€16 and 18 encode E6 oncoprotein, which binds to and induces degradation of the tumour suppressor protein p53