Analysis of p-aminosalicylic acid, its salts and dosage forms, by nonaqueous titration
โ Scribed by James Hunt; Martin I. Blake
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 347 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A major chromogen found in p-aminosalicylic acid and sodium p-aminosalicylate dosage forms was identified to be 3,3'-dihydroxyazoxybenzene. This compound could he produced by oxidation or sunlight irradiation of m-aminophenol, a common impurity of paminosalicylic acid and sodium p-aminosalicylate. M
Barbiturate salts in various dosage forms are determined by liberating the barbituric acid from the salt by passage through a cation exchange resin. Dimethylformamide is used as the solvent. The barbituric acid is titrated visually with 0.1 N sodium methoxide in benzene-methanol. The method is rapid
A photometric titration procedure is described for the determination of a number of phenothiazine derivatives and their dosage forms. An acidic solution of the drug or dosage form is titrated with standard ceric sulfate solution. The end point is determined photometrically at 420 mG. Quantitative re