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Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra

✍ Scribed by Guttman, Miklos; Weis, David D.; Engen, John R.; Lee, Kelly K.

Book ID
121600268
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
584 KB
Volume
24
Category
Article
ISSN
1044-0305

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Deuterated batracylin: deuterium–hydroge
Deuterated batracylin: deuterium–hydrogen exchange during synthesis and mass spectral analysis
✍ Herbert H. Seltzman; Scott E. Fix; Prabhakar Risbood πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 169 KB

## Abstract Deuterium‐labeled analogs of the topoisomerase inhibitor batracylin were prepared for metabolism studies to further its evaluation as an antitumor agent. Established syntheses of unlabeled batracylin were adapted for the preparation of deuterated batracylin that was trideuterated in the