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Analysis of mutations of neurofibromatosis type 1 gene and N-ras gene in acute myelogenous leukemia

✍ Scribed by Young Y Lee; Won S. Kim; Tae J. Jung; Il Y. Choi; Won S. Kim; Yung-J. Bang; Chul W. Jung; Seonyang Park; Byoung K. Kim; Noe K. Kim; Whi J. Yoon; Kyoung S. Cho; H. Phillip Koeffler

Book ID
112212739
Publisher
AlphaMed Press
Year
1995
Tongue
English
Weight
721 KB
Volume
13
Category
Article
ISSN
1066-5099

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## Abstract N‐ras gene activation occurs via single base substitutions in codons 12, 13, and 61. We have developed a rapid screening method, termed allele specific restriction analysis (ASRA), for detection of N‐ras mutations at these three critical codons in acute myeloid leukemia (AML). Patient D