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Analysis of mutational spectra by denaturing capillary electrophoresis

✍ Scribed by Ekstrøm, Per O; Khrapko, Konstantin; Li-Sucholeiki, Xiao-Cheng; Hunter, Ian W; Thilly, William G

Book ID
109946640
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
530 KB
Volume
3
Category
Article
ISSN
1750-2799

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✍ Jens Bjørheim; Marek Minarik; Gustav Gaudernack; Per Olaf Ekstrøm 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 74 KB

Mutations in KRAS exon 1 oncogene are frequently found in colon carcinomas. A correlation between the mutated KRAS and the prognosis and outcome of treatment of colon cancer patients was reported in the literature. The object of our work was to establish a high-throughput method with high sensitivit