Analysis of Ki-ras codon 12 mutations in the duodenal juice of patients with pancreatic cancer
β Scribed by Iguchi, H; Sugano, K; Fukayama, N; Sadamoto, K; Ohkoshi, K; Seo, Y; Tomoda, H; Funakoshi, A; Wakasugi, H; Ohkura, H
- Book ID
- 122936176
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 371 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0016-5085
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Tumor grade of differentiation according to Klceppel (1984).-2Tumor grade, classified as suggested by the American Joint Committee (1977) with T (tumor size), N (nodular status), and M (metastasis), see also te~t.-~SubstiNtion of the wild-type (wt) Ki-ras 12 allele coding for glycine by amino acids
The authors previously found specific mutations of
## Background: Many patients with carcinoma of the pancreas die because their disease is not detected until late in its course. methods that detect these cancers earlier will improve patient outcome. over 80% of pancreatic carcinomas contain mutations in codon 12 of the k-ras gene. screening duoden