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Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors

โœ Scribed by KENICHIROH MUKAWA; SHIGEHIKO FUJII; JUN TAKEDA; KAZUAKI KITAJIMA; KEIICHI TOMINAGA; YOKO CHIBANA; MIKIO FUJITA; KAZUHITO ICHIKAWA; SHIGEKI TOMITA; YUKO ONO; JOHJI IMURA; HITOSHI KAWAMATA; TSUTOMU CHIBA; HIDEYUKI HIRAISHI; AKIRA TERANO; TAKAHIRO FUJIMORI


Book ID
108950352
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
398 KB
Volume
20
Category
Article
ISSN
0815-9319

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Point mutations in codon 12, 13, and 61 of the K-ras gene are an early event in tumorigenesis of colorectal cancer, but the impact of number, type, and position of such mutations on the progression of adenomas as well as the clinical behaviour of colorectal carcinomas is not clearly established. A s