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Analysis of human chromosomal variants by quantitative electron microscopy

✍ Scribed by H. M. Grolomb; G. F. Bahr; D. S. Borgaonkar


Book ID
104705066
Publisher
Springer
Year
1971
Tongue
English
Weight
575 KB
Volume
34
Category
Article
ISSN
0009-5915

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We developed a method for the preparation of ultrathin longitudinal sections of chromosomes enabling TEM studies of whole chromosomes. By using a novel "repeat chill" method of exposing the glass slide and plastic block interface to liquid nitrogen, it was possible to separate consistently hardened