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Analysis of HLA-DQ subregion polymorphisms by sequential restriction endonuclease digestion of genomic DNA


Book ID
123605080
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
157 KB
Volume
17
Category
Article
ISSN
0198-8859

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HLA-DQ polymorphism analyzed by sequenti
✍ Massimo Trucco; Sharon Rosenshine; Isabella Cascino; RenΓ© J. Duquesnoy πŸ“‚ Article πŸ“… 1986 πŸ› Springer-Verlag 🌐 English βš– 696 KB

A direct, physical correspondence between certain Pst I-generated genomic DNA fragments and Taq I-generated fragments, revealed with HLA-DQ alpha or -DQ beta gene probes, has been demonstrated. As an immediate consequence, the nature of the DQ and DX hybridized genes contained in the fragments was e