Proteomics analysis of the neurodegenera
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Kelly Tilleman; Chris Van den Haute; Hugo Geerts; Fred van Leuven; Eddy L. Esman
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Article
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2002
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John Wiley and Sons
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English
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๐ 1 views
Protein tau, a major microtubule-binding protein in the brain, comprises six isoforms generated through alternative mRNA splicing. A dysfunctional form of mutant and normal tau is associated or implicated in the pathogenesis of several neurodegenerative disorders. The neuropathological hallmark of t