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Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos

✍ Scribed by Cornelia Leimeister; Nina Schumacher; Christian Steidl; Manfred Gessler


Book ID
118602015
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
796 KB
Volume
98
Category
Article
ISSN
0925-4773

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Cleidocranial dysplasia (CCD) is an autosomal dominant disease characterized by hypoplasia or aplasia of clavicles, open fontanelles, and other skeletal anomalies. A mouse mutant, shown by clinical and radiographic analysis to be strikingly similar to the human disorder and designated Ccd, was used