Analysis of hereditary component of cancer by use of a familial index by site
✍ Scribed by Bernt Lindelöf; Gunnar Eklund
- Book ID
- 117278975
- Publisher
- The Lancet
- Year
- 2001
- Tongue
- English
- Weight
- 193 KB
- Volume
- 358
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Familial risks for histopathology‐specific cancers have not been determined. We used the nationwide Swedish Family‐Cancer Database on 10.2 million individuals and 1 million tumors to calculate standardized incidence ratios (SIRs) for familial cancers of specific histology and morphology
## Abstract Hereditary non‐polyposis colorectal cancer (HNPCC) is an autosomal dominant disorder characterized by susceptibility to large‐bowel cancer, frequently with early onset and localized in the right colon. Several tumours of other sites may also occur with increased frequency in these famil