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Analysis of growth rate effects on productivity of recombinant Escherichia coli populations using molecular mechanism models

โœ Scribed by Sun Bok Lee; James E. Bailey

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
758 KB
Volume
26
Category
Article
ISSN
0006-3592

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## Abstract At the laboratory scale, sudden step increases from 30 to 42ยฐC can be readily accomplished when expressing heterologous proteins in heatโ€inducible systems. However, for large scaleโ€cultures only slow rampโ€type increases in temperature are possible due to heat transfer limitations, where