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Analysis of ground-state and transition-state effects in enzyme catalysis

โœ Scribed by Menger, F. M.


Book ID
120423983
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
845 KB
Volume
31
Category
Article
ISSN
0006-2960

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Transition-state Ensemble in Enzyme Cata
โœ BUYONG MA; SANDEEP KUMAR; CHUNG-JUNG TSAI; ZENGJIAN HU; RUTH NUSSINOV ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 213 KB

Proteins are not rigid structures; they are dynamic entities, with numerous conformational isomers (substates). The dynamic nature of protein structures ampli"es the structural variation of the transition state for chemical reactions performed by proteins. This suggests that utilizing a transition s