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Transition states, standard states and enzymic catalysis

โœ Scribed by Michael I. Page


Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
456 KB
Volume
11
Category
Article
ISSN
0020-711X

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Transition-state Ensemble in Enzyme Cata
โœ BUYONG MA; SANDEEP KUMAR; CHUNG-JUNG TSAI; ZENGJIAN HU; RUTH NUSSINOV ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 213 KB

Proteins are not rigid structures; they are dynamic entities, with numerous conformational isomers (substates). The dynamic nature of protein structures ampli"es the structural variation of the transition state for chemical reactions performed by proteins. This suggests that utilizing a transition s