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Analysis of glutathione conjugates and related compounds by thermospray mass spectrometry

โœ Scribed by C. E. Parker; J. S. M. de Wit; R. W. Smith; M. B. Gopinathan; O. Hernandez; K. B. Tomer; C. H. Vestal; J. M. Sanders; J. R. Bend

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
747 KB
Volume
15
Category
Article
ISSN
1076-5174

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โœ M. E. Harrison; M. A. Baldwin ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 332 KB

The kinetics of the binding of the neurotoxin acrylamide to the cysteine residue of glutathione has been studied. At 37ยฐC and pH 7.3 the second order rate constant has been determined to be 0.72 f 0.06 mol-' dm3 min-' by thermospray mass spectrometry. The critical energy at pH 115 measured over the