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Analysis of genome-wide CAG/CTG repeats, and at SEF2-1B and ERDA1 in schizophrenia and bipolar affective disorder

✍ Scribed by Vincent, J B; Petronis, A; Strong, E; Parikh, S V; Meltzer, H Y; Lieberman, J; Kennedy, J L

Book ID: 110059000
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 108 KB
Volume: 4
Category: Article
ISSN: 1359-4184
DOI: 10.1038/sj.mp.4000498

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## ~ A new class of disease (including Hunting ton disease, Kennedy disease, and spinocerebellar ataxias types 1 and 3) results from abnormal expansions of CAG trinucleotides in the coding regions of genes. In all of these diseases the CAG repeats are thought to be translated into polyglutamine tr