We have genotyped unrelated French Alsatian schizophrenic and bipolar I disorder (BPD) patients and matched controls for the polymorphic CAG repeats within the genes for spinocerebellar ataxia type 1 (SCA1) and dentatorubral-pallidoluysian atrophy (B37), in order to test their possible involvement i
β¦ LIBER β¦
Association analysis of CAG repeats at theKCNN3 locus in Indian patients with bipolar disorder and schizophrenia
β Scribed by Saleem, Quasar ;Sreevidya, V.S. ;Sudhir, J. ;Savithri, J. Vijaya ;Gowda, Y. ;B-Rao, Chandrika ;Benegal, V. ;Majumder, Partha P. ;Anand, Anuranjan ;Brahmachari, Samir K. ;Jain, Sanjeev
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 113 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0148-7299
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## ~ A new class of disease (including Hunting ton disease, Kennedy disease, and spinocerebellar ataxias types 1 and 3) results from abnormal expansions of CAG trinucleotides in the coding regions of genes. In all of these diseases the CAG repeats are thought to be translated into polyglutamine tr