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Analysis of extrachromosomal DNA from normal and tumor cells

✍ Scribed by V. P. Shelepov; S. L. Arsenin; R. P. Alekhina; T. I. Sukhova; O. I. Serdyuk; V. L. Moiseev; G. B. Raevskaya; A. V. Likhtenshtein


Book ID
110551209
Publisher
Springer US
Year
1995
Tongue
English
Weight
844 KB
Volume
119
Category
Article
ISSN
0007-4888

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## Abstract Extrachromosomal circular DNAs ranging in size from submicroscopic molecules of approximately 100 kb to cytogenetically resolvable structures of 1000+ kb called minute and double‐minute chromosomes have been shown to harbor amplified genes in primary tumor cells, tumor cell lines, and d