Loss of Cyclin B1 followed by downregula
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Xian He Xie; Hee Jung An; Suki Kang; Sunghui Hong; Yoon Pyo Choi; Young Tae Kim;
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Article
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2005
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John Wiley and Sons
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French
⚖ 272 KB
## Abstract Recent studies have shown that Cyclin B1 is overexpressed in various tumor types but present at low levels in normal tissues. To explore the possibility of employing Cyclin B1 as an anticancer target, we knocked down Cyclin B1 in an HeLa cell line using RNA interference (RNAi). Subseque