Changes of G1 cyclins, cdk2, and cyclin A during the differentiation of HL60 cells induced by TPA
โ Scribed by Junko Horiguchi-Yamada; Hisashi Yamada; Shuji Nakada; Keiko Ochi; Tadashi Nemoto
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 857 KB
- Volume
- 132
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Genes encoding cdkl (~34'~''), cyclin A, cyclin B, and the tumor suppressor gene Rb are fundamental regulators of cell cycle progression which associate as a complex with the transcription factor E2F. Expression of many of these proteins has previously been shown to be repressed by okadaic acid, a s
The promyelocytic HL 60 cell line can be used as an in vitro model system to study hematopoetic cell differentiation and inflammatory events. We studied the signal transduction pathway of induced interleukin (IL)-8 expression and compared it with those of tumor necrosis factor alpha (TNF-a), IL-l a,