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Analysis of CHO-K1 cell growth in a fixed bed bioreactor using magnetic resonance spectroscopy and imaging

✍ Scribed by Peter E. Thelwall; Kevin M. Brindle


Book ID
110257781
Publisher
Springer
Year
1999
Tongue
English
Weight
127 KB
Volume
30
Category
Article
ISSN
0920-9069

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We mapped the distribution of dissolved oxygen and mammalian cells in a hollow-fiber bioreactor (HFBR) using 19 F NMR T 1 relaxation time imaging measurements on an infused perfluorocarbon probe molecule and diffusion-weighted 1 H NMR imaging of water. This study shows how cell density influences di