## Abstract Transient expression of rat liver cytochrome P450IA2 cDNA was combined with the use of a shuttle vector as a mutational target to determine the frequency and types of mutation caused by the conversion of aflatoxin B, into genotoxic metabolites within human cells. Ad293 cells were first
Analysis of cellular responses to aflatoxin B1 in yeast expressing human cytochrome P450 1A2 using cDNA microarrays
β Scribed by Yingying Guo; Linda L. Breeden; Wenhong Fan; Lue Ping Zhao; David L. Eaton; Helmut Zarbl
- Book ID
- 113808750
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 408 KB
- Volume
- 593
- Category
- Article
- ISSN
- 0027-5107
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A human lymphoblastoid cell line stably expressing a human cytochrome P4501A2 cDNA was developed. This recombinant cell line displayed P4501A2 protein and estradiol2βhydroxylase activity, neither of which was detected in the parental cell line. The recombinant cell line was also approxi
## Abstract The worldwide human exposure to aflatoxin B~1~ (AFB~1~), particularly in developing countries, remains to be a serious public health concern. Although AFB~1~ is best known as a hepatocarcinogen, epidemiological studies have shown a positive association between human lung cancer occurren