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Analysis of alteration of p75NTR processing and signalling by PS2 mutation and γ-secretase inhibition

✍ Scribed by Yoshio Ito; Azusa Ishii; A. Peter Passmore; Stephen P. McIlroy

Book ID
113812157
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
496 KB
Volume
27
Category
Article
ISSN
0969-9961

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## Abstract The common neurotrophin receptor (p75^NTR^) regulates various functions in the developing and adult nervous system. Cell survival, cell death, axonal and growth cone retraction, and regulation of the cell cycle can be regulated by p75^NTR^‐mediated signals following activation by either