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Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: evidence for association with aggressive and antisocial behavior

โœ Scribed by Rael D. Strous; Nigel Bark; Sam S. Parsia; Jan Volavka; Herbert M. Lachman


Book ID
117334471
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
726 KB
Volume
69
Category
Article
ISSN
0165-1781

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Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-0methyl-transferase t:COMT), which is involved in the metabolism of catecholamines, was mapped to 22q'll and is considered a possible candidate gene for schizophrenia. Recently, we identifi