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Analysis of a 26 kb region on the left arm of yeast chromosome XV

✍ Scribed by Mannhaupt, Gertrud; Vetter, Irene; Schwarzlose, Christa; Mitzel, Sabine; Feldmann, Horst

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 762 KB
Volume: 12
Category: Article
ISSN: 0749-503X
DOI: 10.1002/(sici)1097-0061(199601)12:1<67::aid-yea884>3.0.co;2-f

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✦ Synopsis

In the framework of the EC programme for sequencing yeast chromosome XV, we have determined the nucleotide sequence of a 26 kb region. Subsequent analysis revealed 13 non-overlapping open reading frames, three of which correspond to known yeast genes. A pair of tRNA genes associated with remnant Ty elements were localized in this region. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 2 kb. Protein coding regions occupy 61% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes. The complete nucleotide sequence of the 26 kb segment as depicted in Figure has been deposited at the EBI data library under Accession Number X91067.

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