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Analysis, occurrence, and function of 9-cis-retinoic acid

โœ Scribed by Maureen A. Kane

Book ID
116273653
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
608 KB
Volume
1821
Category
Article
ISSN
1388-1981

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๐Ÿ“œ SIMILAR VOLUMES

Clinical development plan: 9-cis-Retinoi
Clinical development plan: 9-cis-Retinoic acid
๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 892 KB

9-cis-Retinoic acid (9-cis-RA) is a stereo-and photoisomer of all-nuns-retinoic acid (all-nuns-RA) [l]. The cancer chemopreventive activities of the all-trans and 1 3 4 s (13-cis-RA) isomers of retinoic acid [2] are well recognized. The biological effects of retinoids are mediated by intracellular r

Synthesis of 1-[13CD3]-9-cis-retinoic ac
Synthesis of 1-[13CD3]-9-cis-retinoic acid
โœ Youssef L. Bennani ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 430 KB

## Abstract 1โ€[^13^CD~3~]โ€9โ€__cis__โ€Retinoic acid was prepared in 8 steps from 2,6โ€dimethylcyclohexanone. Alkylation of 2,6โ€dimethylcyclohexanone under LiHMDS/MnBr~2~/^13^CD~3~I gave the corresponding labeled 2โ€[^13^CD~3~]โ€2,2,6โ€trimethylcyclohexanone 4 in good yield. Further functionalization of 4