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Analysis by Polymerase Chain Reaction of c-myc Expression in Human Leukemia Cells Induced to Differentiate by Heptachlor and 12-O-Tetradecanoylphorbol-13-acetate

โœ Scribed by A.J. Chuang; P. Yau; K.F. Killam; R.Y. Chuang


Book ID
115642672
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
610 KB
Volume
46
Category
Article
ISSN
0048-3575

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The effect of the skin tumor-promoter TPA (12-0-tetradecanoylphorbol-13-acetate) on expression of cellular proto-oncogenes has been examined in cell lines derived from human urothelium. A single treatment with TPA (1 pg/ml) increased the transcription of clfos and c-myc proto-oncogenes at least 20-f