Analyses of p53 expression pattern and BRCA mutations in patients with double primary breast and ovarian cancer
β Scribed by I. Bruchim; A. Fishman; E. Friedman; I. Goldberg; A. Chetrit; I. Barshack; E. Dekel; G. Hirsh-Yechezkel; B. Modan; J. Kopolovic
- Book ID
- 110758698
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 100 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1048-891X
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We have investigated the impact of BRACA1 and BRACA2 mutations that were frequently identified among Hungarian high-risk breast-ovarian cancer families (Ramus et al., 1997b, AJHG), on the development of breast and ovarian cancer in the general Hungarian population. The prevalence of 3 BRCA1 mutation