Nine novel nonclassical 2,4-diamino-6-methyl-5-thioarylsubstituted-7H-pyrrolo [2,3-d]pyrimidines 2-10 were synthesized as potential inhibitors of dihydrofolate reductase and as antitumor agents. The analogues contain various electron donating and electron withdrawing substituents on the phenylsulfan
โฆ LIBER โฆ
Analogs of tetrahydrofolic acid. XXI. Synthesis of 6-bromomethyl-5-(p-chlorophenyl)-2,4-diaminopyrimidine and its evaluation as a dihydrofolic reductase inhibitor
โ Scribed by B. R. Baker; Johannes H. Jordaan
- Book ID
- 112121273
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1965
- Tongue
- English
- Weight
- 414 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0022-152X
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